Dolo 650 – Uses, Ingredients, Dosage, Side Effects, Interactions

Dolo 650 is a commonly used pain reliever medication that contains paracetamol as its active ingredient. In this article, we will discuss in detail about the uses, side effects, interactions, dosage, missed dose, overdose, and frequently asked questions (FAQs) about Dolo 650.

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Active ingredient in Dolo 650

Dolo 650 contains the active ingredient paracetamol, also known as acetaminophen, which is a widely used pain reliever and fever reducer. The exact mechanism of how paracetamol works is not fully understood, but it is believed to work by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain and fever.

Paracetamol works primarily in the brain, where it reduces the sensitivity of pain receptors and helps to lower fever by acting on the hypothalamus, which is the part of the brain that regulates body temperature.

 

Uses of Dolo 650

Dolo 650 is primarily used to relieve pain and reduce fever. It is commonly used to treat conditions such as:

  1. Headache
  2. Toothache
  3. Menstrual cramps
  4. Arthritis
  5. Muscle pain
  6. Backache
  7. Fever
  8. Common cold and flu

Dolo 650 works by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain and fever.

Side Effects of Dolo 650

Dolo 650 is a commonly used pain reliever that is generally safe for most people when used as directed. However, like any medication, it can cause side effects in some individuals. Here are some of the common side effects of Dolo 650:

  1. Nausea and vomiting
  2. Stomach pain and discomfort
  3. Diarrhea
  4. Allergic reactions such as rashes and itching
  5. Dizziness and lightheadedness
  6. Sleepiness and fatigue
  7. Dry mouth
  8. Sweating

In rare cases, Dolo 650 can cause serious side effects, such as liver damage. Symptoms of liver damage may include dark urine, yellowing of the skin or eyes, and abdominal pain.

If you experience any of these serious side effects or have concerns about the side effects of Dolo 650, it is important to consult with your healthcare provider. It is also important to follow the recommended dosage and not exceed the maximum daily dose of 4,000 milligrams to avoid potential side effects and overdose.

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Dolo 650 and its Interaction with Other Medications

Dolo 650 can interact with other medications and cause adverse effects. Some medications that can interact with Dolo 650 include:

  1. Other pain relievers such as aspirin and ibuprofen
  2. Blood thinners such as warfarin
  3. Medications used to treat high blood pressure such as enalapril
  4. Medications used to treat seizures such as phenytoin

You should inform your healthcare provider about all the medications you are taking before taking Dolo 650.

Dolo 650 Dosage

The recommended dosage of Dolo 650 depends on the age, weight, and condition of the individual. It is important to follow the recommended dosage and not exceed the maximum daily dose of 4,000 milligrams to avoid potential side effects and overdose.

The standard dosage for adults is 650 milligrams to 1 gram (1000 milligrams) every 4-6 hours, up to a maximum of 4 grams per day. It is recommended to take Dolo 650 with a full glass of water.

For children, the dosage is based on their weight and should be determined by a healthcare provider. The recommended pediatric dosage is usually 10-15 milligrams per kilogram of body weight every 4-6 hours, up to a maximum of 65 milligrams per kilogram per day.

It is important to note that taking more than the recommended dose of Dolo 650 can lead to liver damage, which can be life-threatening. If you are unsure about the appropriate dosage for your age or condition, consult with your healthcare provider.

 Missed Dose of Dolo 650

If you miss a dose of Dolo 650, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose of Dolo 650 to make up for the missed dose.

Overdose of Dolo 650

Taking an overdose of Dolo 650 can cause serious harm, including liver damage and even death. Symptoms of a Dolo 650 overdose may include:

  1. Nausea and vomiting
  2. Stomach pain
  3. Loss of appetite
  4. Sweating
  5. Jaundice

If you suspect a Dolo 650 overdose, seek immediate medical attention.

FAQs (Frequently asked Questions) on Dolo 650

Here are some frequently asked questions (FAQs) about Dolo 650:

  1. What is Dolo 650 used for?

Dolo 650 is used to relieve pain and reduce fever. It is commonly used to treat conditions such as headache, toothache, menstrual cramps, arthritis, muscle pain, backache, fever, and common cold and flu.

  1. What is the active ingredient in Dolo 650?

The active ingredient in Dolo 650 is paracetamol, also known as acetaminophen.

  1. How does Dolo 650 work?

Dolo 650 works by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain and fever.

  1. Is Dolo 650 safe during pregnancy and breastfeeding?

Dolo 650 is generally safe during pregnancy and breastfeeding, but you should consult your healthcare provider before taking it.

  1. Can I drink alcohol while taking Dolo 650?

Drinking alcohol while taking Dolo 650 can increase the risk of liver damage.

  1. Can I take Dolo 650 with food?

You can take Dolo 650 with or without food.

  1. Can I give Dolo 650 to my child?

You should consult your healthcare provider before giving Dolo 650 to a child. The recommended pediatric dosage is based on the weight of the child and should be determined by a healthcare provider.

  1. How long can I take Dolo 650?

You should not take Dolo 650 for more than 5 days without consulting your healthcare provider.

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  1. What are the side effects of Dolo 650?

Some of the common side effects of Dolo 650 include nausea and vomiting, stomach pain and discomfort, diarrhea, allergic reactions such as rashes and itching, and liver damage (rare).

  1. What should I do if I miss a dose of Dolo 650?

If you miss a dose of Dolo 650, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose of Dolo 650 to make up for the missed dose.

  1. What should I do if I suspect a Dolo 650 overdose?

If you suspect a Dolo 650 overdose, seek immediate medical attention. Symptoms of a Dolo 650 overdose may include nausea and vomiting, stomach pain, loss of appetite, sweating, and jaundice. Taking an overdose of Dolo 650 can cause serious harm, including liver damage and even death.

You should not take Dolo 650 for more than 5 days without consulting your healthcare provider.

In conclusion, Dolo 650 is a widely used pain reliever that can be purchased over the counter. However, it is important to use it responsibly and follow the recommended dosage to avoid potential side effects and interactions with other medications.

It is also important to note that while Dolo 650 is effective at reducing pain and fever, it does not treat the underlying condition causing the symptoms. Therefore, it is important to consult with your healthcare provider if your symptoms persist or worsen.

Additionally, it is important to be aware of the signs and symptoms of liver damage, which is a rare but serious side effect of Dolo 650. These symptoms include dark urine, yellowing of the skin or eyes, and abdominal pain.

Finally, while Dolo 650 is generally safe for most people, it is not recommended for individuals with certain health conditions such as liver disease, kidney disease, or a history of alcohol abuse. As with any medication, it is important to consult with your healthcare provider before taking Dolo 650 if you have any underlying health conditions or are taking any other medications.

Clinical Research Studies on Dolo 650

Clinical studies have shown that paracetamol is effective in reducing pain and fever in a variety of conditions, including headache, toothache, menstrual cramps, arthritis, muscle pain, backache, fever, and common cold and flu. Paracetamol is considered safe and effective when used as directed, but it is important to follow the recommended dosage and not exceed the maximum daily dose of 4,000 milligrams to avoid potential side effects and overdose.

In addition, paracetamol has been extensively studied and has been found to have a low risk of causing adverse events when used at the recommended dose. However, it is important to note that prolonged or excessive use of paracetamol can lead to liver damage, which can be life-threatening. Therefore, it is important to use paracetamol as directed and to consult with a healthcare provider if you have any concerns or questions about its use.

Dolo 650, which contains the active ingredient paracetamol or acetaminophen, has been the subject of numerous clinical studies over the years. Here are some of the key findings from these studies:

  1. Pain Relief: A study published in the Journal of Pain and Symptom Management in 2016 found that paracetamol was effective in reducing pain in cancer patients. The study also found that paracetamol had no significant side effects in these patients.
  2. Fever Reduction: A study published in the Cochrane Database of Systematic Reviews in 2013 found that paracetamol was effective in reducing fever in children with acute febrile illness. The study also found that paracetamol had a low risk of adverse events in these children.
  3. Headache Relief: A study published in the Journal of Headache and Pain in 2019 found that paracetamol was effective in reducing headache intensity and improving headache-related disability in patients with tension-type headache.
  4. Safety and Tolerability: A study published in the International Journal of Clinical Pharmacology and Therapeutics in 2006 found that paracetamol was well-tolerated and had a low risk of adverse events when used at the recommended dose.

To sum up, clinical studies have shown that paracetamol, the active ingredient in Dolo 650, is effective in relieving pain and reducing fever, and is generally safe and well-tolerated when used as directed. However, it is important to use paracetamol only as directed and to consult with a healthcare provider if you have any questions or concerns about its use.

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