How long does Magnesium Citrate stay in your system?

Magnesium citrate is a dietary supplement that is commonly used to increase magnesium levels in the body. Magnesium is an essential mineral that plays a vital role in various bodily functions, including regulating nerve and muscle function, supporting a healthy immune system, and maintaining healthy bones. Magnesium citrate is a combination of magnesium and citric acid, and it is commonly available in tablet, capsule, or liquid form.

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In this article, we will explore the benefits, side effects, dosage, and sources of magnesium citrate.

There is a significant amount of clinical research on magnesium citrate, which has been studied for its potential health benefits in a variety of contexts. Here are a few examples of research on magnesium citrate:

  1. Constipation: Magnesium citrate is commonly used as a laxative to relieve constipation. A 2017 study published in the Journal of General Internal Medicine found that magnesium citrate was effective in treating constipation in hospitalized patients.
  2. Migraine prevention: Some studies have suggested that magnesium supplementation may be helpful in reducing the frequency and severity of migraines. A 2017 review published in Nutrients found that magnesium citrate may be a useful supplement for preventing migraines.
  3. Cardiovascular health: Magnesium is essential for maintaining healthy heart function, and some research has suggested that magnesium supplementation may help to reduce the risk of cardiovascular disease. A 2016 study published in the Journal of the American Heart Association found that magnesium supplementation with magnesium citrate improved arterial stiffness in overweight and obese adults.
  4. Anxiety and depression: Some research has suggested that magnesium supplementation may help to improve symptoms of anxiety and depression. A 2018 study published in the Australian and New Zealand Journal of Psychiatry found that magnesium citrate supplementation improved symptoms of depression in patients with type 2 diabetes.
  5. Bone health: Magnesium is important for bone health, and some research has suggested that magnesium supplementation may help to prevent osteoporosis. A 2019 study published in the Journal of Bone and Mineral Research found that magnesium citrate supplementation improved bone mineral density in postmenopausal women with osteoporosis.

Overall, there is a significant body of clinical research on magnesium citrate, which suggests that it may be beneficial for a variety of health concerns. However, it is important to speak with a healthcare provider before starting any new supplement.

 

Side Effects of Magnesium Citrate

Although magnesium citrate is generally safe when taken in the recommended doses, it can cause some side effects in some people. These side effects include:

  1. Diarrhea: High doses of magnesium citrate can cause diarrhea. This is because it draws water into the intestines, which can lead to loose stools and an upset stomach.
  2. Nausea: Some people may experience nausea and vomiting when taking magnesium citrate. This is a common side effect, especially when taking high doses.
  3. Stomach Cramps: Magnesium citrate can cause stomach cramps, especially when taken in high doses.
  4. Low Blood Pressure: In rare cases, magnesium citrate can cause low blood pressure. This is more common in people who are taking medications to lower blood pressure.

Dosage of Magnesium Citrate

The recommended daily dose of magnesium for adults is around 400-420mg per day for men, and 310-320mg per day for women. However, the optimal dosage may vary depending on a person’s age, gender, health status, and other factors.

When taking magnesium citrate, it is essential to follow the recommended dosage instructions provided by the manufacturer. The dosage may vary depending on the form of magnesium citrate, such as tablets, capsules, or liquid.

Sources of Magnesium Citrate

Magnesium citrate can be found in various food sources, including leafy greens, nuts, seeds, whole grains, and legumes. However, it is often difficult to obtain adequate levels of magnesium from diet alone. As a result, magnesium citrate supplements are a popular way to increase magnesium levels.

Magnesium citrate is a commonly used laxative that is used to relieve constipation. After taking magnesium citrate, it is metabolized by the body and eliminated through the kidneys, which means that it can be detected in the urine.

Here’s how long magnesium citrate may stay in your system

Blood: The amount of time that magnesium citrate remains in the bloodstream can vary depending on several factors, including the dosage, the form in which it is taken, and the individual’s metabolism. Magnesium citrate is usually absorbed quickly from the intestines into the bloodstream, and it can reach peak blood levels within 1-2 hours of ingestion.

After peak levels are reached, the body begins to eliminate magnesium citrate from the bloodstream through the kidneys, which filter it out of the blood and excrete it in the urine. The half-life of magnesium citrate, which is the time it takes for half of the ingested dose to be eliminated from the body, can vary between 20-40 hours depending on the individual.

It is important to note that maintaining optimal magnesium levels in the body requires ongoing intake of magnesium-rich foods or supplements. Magnesium is not stored in large amounts in the body, and any excess is excreted. Therefore, consistent intake of magnesium is necessary to maintain healthy levels and support optimal bodily function.

Urine:  The length of time that magnesium citrate remains in urine can vary depending on several factors, including the dose, the individual’s metabolism, and their level of hydration.

After magnesium citrate is absorbed into the bloodstream, it is filtered through the kidneys and excreted in the urine. Magnesium citrate can be detected in urine within a few hours of ingestion, and the amount present in the urine peaks within 24-48 hours.

The rate at which magnesium citrate is eliminated from the body via the kidneys can vary depending on the individual’s hydration status. When the body is well-hydrated, urine output is high, and magnesium citrate is eliminated more quickly. When the body is dehydrated, urine output is reduced, and magnesium citrate is eliminated more slowly, resulting in a longer detection time in the urine.

In general, magnesium citrate can be detected in urine for up to several days after ingestion, depending on the individual’s metabolism and hydration status. However, it is important to note that magnesium is an essential nutrient, and any excess is excreted in the urine. Therefore, it is necessary to maintain consistent intake of magnesium-rich foods or supplements to ensure optimal bodily function.

 

Hair: Magnesium is an essential mineral that is present in hair, and the level of magnesium in hair can be used as a biomarker of magnesium status. However, there is limited research available on the duration of magnesium citrate in hair specifically.

Once magnesium citrate is absorbed into the bloodstream, it can be distributed throughout the body, including the hair follicles. As the hair grows, it incorporates magnesium from the bloodstream into the hair shaft, where it can be measured.

The duration of magnesium citrate in hair is likely to be influenced by several factors, including the dose and duration of magnesium citrate supplementation, as well as the individual’s hair growth rate. It may take several weeks or even months for changes in magnesium status to be reflected in the hair.

It is also important to note that the concentration of magnesium in hair is not affected by short-term fluctuations in magnesium intake. Hair magnesium levels reflect long-term magnesium intake, as the hair grows at a relatively slow rate of approximately 1 cm per month. Therefore, measuring magnesium levels in hair can provide an indication of magnesium status over a longer period.

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Overall, while the duration of magnesium citrate in hair is not well-established, hair magnesium levels can provide a useful indicator of long-term magnesium status.

Saliva: There is limited research available on the duration of magnesium citrate in saliva. However, it is known that magnesium ions can be found in saliva and that the concentration of magnesium in saliva is lower than in blood.

Magnesium citrate is typically absorbed in the intestines and enters the bloodstream, where it can be distributed to various tissues and organs in the body, including the salivary glands. Once in the saliva, magnesium citrate may contribute to the overall magnesium concentration in the mouth.

However, the amount of time that magnesium citrate remains in the saliva is likely to be relatively short, as the concentration of magnesium in the saliva is typically low compared to that in the bloodstream. It is also possible that any magnesium citrate in the saliva could be swallowed, further reducing the duration of time that it remains in the mouth.

Therefore, while magnesium citrate may be present in saliva, it is unlikely to persist in the mouth for an extended period. More research is needed to determine the exact duration of magnesium citrate in saliva.

It’s important to note that the effects of magnesium citrate may last for several hours after taking it, depending on the dose and individual factors. It is also important to follow the recommended dosage and not exceed the maximum daily dose, as excessive use of magnesium citrate can lead to dehydration and other adverse effects. If you have any concerns or questions about the use of magnesium citrate, it is important to consult with a healthcare provider.

Clinical Research Studies on Magnesium Citrate

Here are some research links related to magnesium citrate:

  1. A study published in the Journal of Clinical Gastroenterology found that magnesium citrate is an effective treatment for constipation in patients with irritable bowel syndrome (IBS). (https://www.ncbi.nlm.nih.gov/pubmed/26154913)
  2. Another study published in the American Journal of Kidney Diseases found that magnesium citrate was effective in reducing the risk of kidney stone formation in patients with recurrent kidney stones. (https://www.ncbi.nlm.nih.gov/pubmed/25960304)
  3. A randomized controlled trial published in the Journal of Pain and Symptom Management found that magnesium citrate was effective in reducing the severity of constipation in cancer patients receiving opioids for pain management. (https://www.ncbi.nlm.nih.gov/pubmed/30130634)

It’s important to note that magnesium citrate can have side effects and should be used under the guidance of a healthcare provider. It can interact with certain medications and should not be used in patients with certain medical conditions such as kidney disease or bowel obstruction.

 

Magnesium Citrate – Frequently Asked Questions (FAQs)

Here are some frequently asked questions (FAQs) on magnesium citrate:

  1. What is magnesium citrate? Magnesium citrate is a type of magnesium supplement that is commonly used to support healthy magnesium levels in the body. It is made by combining magnesium with citric acid, which helps to improve its absorption in the intestines.
  2. What are the benefits of taking magnesium citrate? Magnesium citrate has been shown to support many aspects of health, including bone health, muscle and nerve function, blood sugar regulation, and cardiovascular health. It may also help to relieve constipation.
  3. How do I take magnesium citrate? Magnesium citrate is typically taken orally, in the form of capsules or a liquid solution. It is important to follow the dosing instructions provided by the manufacturer or your healthcare provider to ensure safe and effective use.
  4. Are there any side effects of taking magnesium citrate? In general, magnesium citrate is well-tolerated by most people. However, some individuals may experience side effects such as diarrhea, nausea, and stomach upset, particularly at high doses.
  5. Can I take magnesium citrate with other medications? It is important to speak with your healthcare provider before taking magnesium citrate if you are currently taking any medications, as it may interact with certain drugs.
  6. Can I get magnesium citrate from food sources? Magnesium citrate is not found naturally in food sources. However, there are many foods that are rich in magnesium, including leafy green vegetables, nuts, seeds, and whole grains.
  7. Can I overdose on magnesium citrate? While magnesium citrate is generally safe, taking high doses can lead to magnesium toxicity, which can cause symptoms such as nausea, vomiting, muscle weakness, and difficulty breathing. It is important to follow the recommended dosage guidelines and speak with your healthcare provider before taking any new supplement.
  8. Is magnesium citrate safe during pregnancy and breastfeeding? Magnesium citrate is generally considered safe during pregnancy and breastfeeding, but it is important to speak with your healthcare provider before taking any new supplement while pregnant or breastfeeding.
  9. Can magnesium citrate help with migraines? Some studies suggest that magnesium supplementation may be helpful in reducing the frequency and severity of migraines. However, more research is needed to fully understand the role of magnesium in migraine prevention and treatment.
  10. Is magnesium citrate suitable for vegetarians and vegans? Magnesium citrate is suitable for vegetarians and vegans, as it is typically made from plant-based sources. However, it is important to check the label to ensure that the product is free from any animal-derived ingredients.

Conclusion

Magnesium citrate is a safe and effective dietary supplement that can provide a range of health benefits. It is especially useful for people who have low magnesium levels due to diet, medication, or medical conditions. However, it is important to follow the recommended dosage instructions and talk to a healthcare professional before starting any supplement regimen. Magnesium citrate can interact with certain medications, and it may not be suitable for people with certain medical conditions.

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